胸腔血管肉瘤的发生率和生存率:来自基于人口的癌症注册表的流行病学证据
Niels Michael Dörr-Jerat1,2, Ina Wellmann3, Franziska Rees3
1Department of Thoracic Surgery, Martha-Maria Hospital Halle-Dölau, 06120 Halle, Germany.
Cancers
|February 27, 2026
概括
胸腔血管肉瘤是一种罕见的癌症. 患有这种疾病的女性的预后通常比男性更好,瘤的位置显著影响生存结果.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 病理学 病理学 病理学
背景情况:
- 胸腔血管肉瘤是一种异常罕见且具有攻击性的恶性瘤.
- 这项研究调查了胸腔血管瘤的发病率和生存模式,区分了初级和二级类型.
研究的目的:
- 为了确定胸腔血管瘤的发病率在德国北莱-威斯特伐利亚,德国.
- 分析患有胸腔血管瘤的患者的生存结果,考虑初级与二级起源以及患者人口统计数据.
- 为了确定影响胸腔血管肉瘤生存的预后因素.
主要方法:
- 利用来自北莱-威斯特法利亚 (2008-2023) 的基于人口的癌症登记数据.
- 包括初级和二级胸部血管瘤 (ICD-O-3: 9120/3; 地形 C34,C38,C44.51,C49.3,C50).
- 计算了年龄标准化的发病率,并使用卡普兰-梅尔曲线进行了生存分析.
主要成果:
- 分析了421例;90%的患者是女性 (n=379).
- 年龄标准化发病率为男性0.25/百万/年,女性1.5/百万/年.
- 五年总生存率为38.5%;女性 (41.1%) 的生存率比男性 (12.0%) 更好.
- 瘤拓是一个关键的预后因素,肺部,中,心脏和多发性血管瘤显示出最糟糕的结果,特别是在男性中.
结论:
- 胸腔血管肉瘤是一种罕见的恶性瘤,预后通常不佳.
- 患有胸腔血管肉瘤的女性,无论初级或二级状态如何,与男性相比,表现出更好的生存前景.
- 瘤的解剖位置 (地形) 是胸腔血管肉瘤预后的最重要的决定因素.
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