相关实验视频

Updated: Feb 28, 2026

Ultrasonographic Evaluation of Breast Cancer-related Lymphedema

Ultrasonographic Evaluation of Breast Cancer-related Lymphedema

Published on: January 12, 2017

运动对乳腺癌患者有免疫效应吗? 一个系统性审查和元分析

Celia García-Chico¹, María Merino-País¹, Simone Lista¹

¹i+HeALTH Strategic Research Group, Department of Health Sciences, Miguel de Cervantes European University, 47012 Valladolid, Spain.

|February 27, 2026

概括

运动不会显著改变乳腺癌患者或幸存者的循环免疫细胞. 这表明运动是安全的,可能会通过细胞计数以外的机制影响免疫力.

科学领域:

在瘤学瘤学.
免疫学免疫学免疫学
运动科学运动科学

背景情况:

运动与降低乳腺癌 (BC) 风险和改善生存率有关.
精确的生物机制,特别是免疫调节,需要进一步阐明.
运动可能会影响瘤微环境中的全身免疫和免疫细胞透.

研究的目的:

系统地审查和元分析运动对乳腺癌患者免疫细胞和相关标记物的影响.
评估运动干预后自然杀手细胞,T细胞亚群和B细胞的变化.

主要方法:

按照PRISMA指南进行系统审查和元分析.
搜索了四个主要的数据库 (PubMed,科学网,Scopus,Cochrane图书馆) 相关的随机对照试验.
包括18项研究 (911名参与者),并对特定免疫细胞结果进行了元分析.

主要成果:

运动干预措施没有在循环自然杀手细胞数量或活动中产生显著变化.
没有观察到对T细胞亚群 (CD3+,CD4+,CD8+) 或B细胞水平的显著影响.
这些发现表明,运动对静止循环免疫细胞群体没有一致的影响.

结论:

对于乳腺癌患者和幸存者来说,运动似乎在免疫学上是安全的,因为它涉及循环免疫细胞的数量.
运动的好处可能通过超出改变休息循环免疫细胞种群的机制来发挥作用.
需要进一步的大规模研究才能充分理解运动在乳腺癌中的复杂免疫效应.

关键词:

这是T-淋巴细胞.乳腺新生瘤的发生.免疫疗法免疫疗法自然杀手细胞是自然杀手细胞.身体活动身体活动阻力训练可以进行抵抗训练.瘤微环境是一个微环境.

更多相关视频

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse

The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse

Published on: May 31, 2016

相关概念视频

Exercise and Cardiovascular Response

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...

Cancer Prevention

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...