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Updated: May 8, 2026

An Optogenetic Approach for Assessing Formation of Neuronal Connections in a Co-culture System
11:22

An Optogenetic Approach for Assessing Formation of Neuronal Connections in a Co-culture System

Published on: February 17, 2015

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高纯度的脂素通过调节SIRT1-PGC-1α通路来改善人类皮质神经元功能

Sung-Min Jeon1, Stanley Cho2, Yoon-Seob Lee3,4

  • 1Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.

Brain sciences
|February 27, 2026
PubMed
概括

较高的脂素 (PS) 纯度通过促进SIRT1和PGC-1α来增强人类皮质神经元中的神经保护. 这种改善的神经元健康和线粒体功能对阿尔茨海默氏病 (AD) 模型显示出希望.

关键词:
诱导Aβ42的阿尔茨海默氏病模型.在PS纯度上,纯度为PS.在SIRT1-PGC-1α轴上.衰老的衰老 衰老的衰老大脑健康 大脑健康线粒体质量控制的质量控制酸丁氨酸 (PS) 是一种酸丁氨酸.

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