作为智利功能性食品的马基:抗氧化生物活性,营养价值和健康应用
Caterina Tiscornia1, Enrique Lorca2,3, Carolina Estremadoyro1
1Escuela de Nutrición y Dietética, Universidad Finis Terrae, Santiago 7501015, Chile.
Antioxidants (Basel, Switzerland)
|February 27, 2026
概括
富含抗氧化剂的maqui果显示出通过减少炎症和改善代谢健康来治疗慢性疾病的潜力. 需要进一步的临床试验来确认其益处并优化交付.
科学领域:
- 营养科学 营养科学
- 药理学 药理学是指药理学的学科.
- 食品科学 食品科学 食品科学
背景情况:
- 马基 (Aristotelia chilensis) 是一种智利的果,富含化合物,特别是海豚素 (delphinidin) 酸盐.
- 这些化合物具有显著的抗氧化和抗炎性质,促使人们对maqui作为一种功能性食物产生兴趣.
- 研究正在探索maqui的生物机制,包括Nrf2通路激活和对心脏代谢,脏和血管健康的影响.
研究的目的:
- 审查关于maqui的营养和生物活性成分的证据.
- 分析其抗氧化和抗炎机制以及生物可用性.
- 探索其在预防和治疗慢性非传染性疾病中的临床应用.
主要方法:
- 临床前和临床研究的文献综述.
- 对maqui的营养状况进行分析,包括delphinidins,纤维和微量营养素.
- 检查maqui对Nrf2-HO-1和NF-κB等关键信号通路的影响.
主要成果:
- 马基表现出丰富的海豚素含量,纤维和抗氧化剂,调节氧化应激和炎症途径.
- 临床前和早期临床数据表明心脏代谢和脏保护作用.
- 有证据表明,血糖控制,脂质配置,氧化应激和内皮功能有所改善.
结论:
- 由于其抗氧化和抗炎性质,maqui显示出作为一种功能性食物的巨大潜力.
- 它在人类健康,特别是慢性疾病的应用是有前途的.
- 需要进一步严格的临床试验和增强生物利用性的配方来确定其治疗作用.
关键词:
亚里士多德 (Aristotelia chilensis) 是一种植物.它们是安托西安氨酸.抗氧化剂 抗氧化剂是一种抗氧化剂.鱼类的鱼类是什么?这是一种炎症炎症炎症炎症.氧化应激是一种氧化应激.更多相关视频
14:39Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
4.5K
07:05Author Spotlight: Eco-Friendly Extraction of Bioactive Compounds Using Polyol-Based Microwave-Assisted Techniques
Published on: August 23, 2024
3.0K
相关概念视频
02:59Cancer Prevention
8.3K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
8.3K
01:13Bioavailability: Overview
4.7K
Bioavailability refers to the proportion of an unaltered drug that, after administration, enters the systemic circulation and can be distributed to the desired action site. Factors such as gastrointestinal (GI) absorption and liver biotransformation influence the bioavailability of a drug when it is administered orally. When a drug is administered intravenously, it enters the systemic circulation directly; by definition, its bioavailability is assumed to be 100%. The bioavailability of an...
4.7K
01:17Bioavailability: Overview
597
Bioavailability refers to the proportion of an administered drug that reaches the systemic circulation in its active, unaltered form. It is a crucial pharmacokinetic parameter that determines the effectiveness of a drug in achieving its intended therapeutic outcomes. The route of administration significantly influences bioavailability, with intravenous administration achieving 100% bioavailability as the drug directly enters the bloodstream. In contrast, oral administration often results in...
597
01:22Bioavailability: Influencing Factors
482
Bioavailability refers to the extent and rate at which a drug reaches systemic circulation in its active form. Extent refers to the amount of the drug that makes it into circulation, while rate is the speed at which it enters circulation. It is influenced by several factors critical for optimizing drug formulations, dosing regimens, and therapeutic outcomes.Physicochemical properties of drugs and formulationsThe solubility, stability, and dissolution rate of a drug significantly impact its...
482
01:23Factors Influencing Bioavailability: First-Pass Elimination
8.3K
When a drug is taken orally, it undergoes a journey starting from the gastrointestinal (GI) tract, passing through the portal vein, reaching the liver, and finally entering the systemic circulation. This process involves the absorption of the drug across the GI tract. The liver is the primary site for metabolizing the drug, with some metabolism also occurring in the gut wall. This journey significantly reduces the quantity of the drug that reaches the systemic circulation, a phenomenon known as...
8.3K
01:22Bioavailability Enhancement: Determination and Conceptual Approaches in Overcoming Bioavailability Problems
270
Body:Bioavailability is a critical pharmacological concept that measures the extent and rate at which an active drug ingredient or therapeutic moiety enters the systemic circulation, remaining unchanged. It's a pivotal factor in determining a drug's efficacy and safety.The Biopharmaceutics Classification System (BCS) plays an essential role in drug development by categorizing drugs into four classes based on their solubility and permeability. This classification aids in understanding drug...
270