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对抗IL-17A可减少血管炎症和减轻氧化应激形成,但不能显著改善一周安二醇治疗引起的血管功能障碍

Rebecca Jung1,2, Annika Lehmann1,2, Tanja Knopp1,2

  • 1Center for Cardiology-Cardiology I, University Medical Center Mainz, 55131 Mainz, Germany.

Antioxidants (Basel, Switzerland)
|February 27, 2026
PubMed
概括

介素-17A (IL-17A) 阻断在小鼠中部分降低了血管早期炎症和来自血管素II (Ang II) 的氧化应激. 然而,它并没有防止血管功能障碍,这表明对于自身免疫相关的心血管问题需要联合治疗.

关键词:
ангиотензин II 诱导的血管功能障碍和炎症这种药物是17A型中白素-17A.骨髓状细胞是骨髓状细胞的组成部分.血管疾病是血管疾病.

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