双边大腿骨轴骨折与长期双酸盐治疗相关
Symeon Naoum1, Sam Nahas1, James Duncan1
1Department of Trauma and Orthopaedics, Royal Berkshire Hospital, Reading RG1 5AN, UK.
Diagnostics (Basel, Switzerland)
|February 27, 2026
概括
长时间使用双酸盐会导致非典型的股骨骨折 (AFFs). 这个案例显示磁共振成像 (MRI) 检测了早期的压力损伤,有助于诊断患有大腿疼痛的患者.
科学领域:
- 整形外科 整形外科 整形外科
- 放射学 放射学是一门学科.
- 药理学 药理学是指药理学的学科.
背景情况:
- 非典型的股骨骨折 (AFFs) 是与延长双酸盐治疗相关的罕见并发症.
- 这些骨折可以表现为压力损伤,特别是在长期使用阿伦德罗纳特时.
研究的目的:
- 介绍长期服用阿伦德罗纳特的患者双边股骨轴应力损伤的成像研究结果.
- 突出MRI在识别早期不完整AFF的诊断实用性.
主要方法:
- 一个64岁的绝经后妇女的案例介绍,她使用了阿伦德罗纳特4年.
- 使用磁共振成像 (MRI) 评估大腿骨轴应力损伤.
- 与放射性成像相关联的MRI发现.
主要成果:
- 核磁共振扫描显示了3级压力损伤,侧皮层参与和大脑髓,表明早期不完整的AFFs.
- 放射图证实了一种不典型的横断骨折模式,侧面皮层口.
- 图像检测结果先于完全骨折.
结论:
- 在AFF完成之前,MRI对于早期检测与压力相关的变化是有价值的.
- 早期识别这些成像特征对于及时诊断和治疗修改至关重要.
- 及时干预可以改善抗吸收疗法患者出现前兆大腿疼痛的结果.
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