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与对比增强的乳房影像与对比增强的乳房影像. 评估新辅助化疗反应的乳房MRI:一项前性临床比较研究
Omer Acar1, Çağdaş Rıza Açar2, İhsan Sebnem Orguc2
1Department of Medical Oncology, Mardin Training and Research Hospital, Mardin 47200, Turkey.
Diagnostics (Basel, Switzerland)
|February 27, 2026
概括
与对比度增强的乳房显微镜 (CEM) 在评估新辅助化疗 (NAC) 后的残留瘤大小和病理完整反应方面显示了与乳房MRI相似的准确性. CEM提供了一个实用的替代方案,特别是当MRI无法使用时.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 新辅助化疗 (NAC) 是乳腺癌的标准治疗方法.
- 准确评估治疗反应对于患者管理至关重要.
- 乳房MRI是目前评估NAC反应的标准.
研究的目的:
- 为了比较对比度增强的乳房显微镜 (CEM) 与乳房MRI.
- 评估NAC后的残留瘤大小和病理完整反应 (pCR).
- 为了确定CEM是否是MRI的可行的替代方案,以评估反应.
主要方法:
- 74名接受NAC.的乳腺癌患者的前性研究.
- 患者在NAC之前和之后接受了CEM和乳房MRI.
- 剩余瘤大小和pCR与组织病理学发现进行了比较.
主要成果:
- 在84.7%的病例中,CEM估计剩余瘤大小在组织病理学±1厘米范围内,而MRI则为76.4%.
- 对于预测PCR,CEM的灵敏度 (91.3%) 比MRI更高.
- 对CEM而言,与组织病理学的一致性高于MRI.
结论:
- 在评估NAC反应方面,CEM的性能与乳房MRI相美.
- 对于预测pCR,CEM表现出数值上更高的灵敏度.
- CEM是一种实用且易于使用的MRI替代方案,用于响应评估.
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