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新型GC373类SARS-CoV-2主要蛋白酶抑制剂的设计和体外评估

Aleksandra A Kuznetsova1, Aleksandr P Makhin2, Anatoliy A Bulygin1

  • 1Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.

Current issues in molecular biology
|February 27, 2026
PubMed
概括

针对SARS-CoV-2主要蛋白酶 (Mpro) 的新型皮相聚体抑制剂显示出对抗病毒开发的前景. 这些化合物表现出微分子活性,为未来针对新兴变种的COVID-19治疗提供了潜力.

关键词:
在 COVID-19 疫情中,这就是SARS-CoV-2病毒.抗病毒药物设计 抗病毒药物设计这是一种皮多米米特抑制剂.综合合成是一种合成.

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