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多米和空间分析识别了一种与胰腺管道腺癌中的微环境重塑相关的上皮DKK1

Jiajia Xu1,2, Kaiqiang Qian3, Yanyu Ding1,2

  • 1Department of Immunology, School of Basic Medical Sciences, Center for Big Data and Population Health of IHM, Anhui Medical University, Hefei 230032, China.

Current issues in molecular biology
|February 27, 2026
PubMed
概括

Dickkopf-1 (DKK1) 是一种表皮细胞调节剂,驱动胰腺癌的进展和免疫变化. 向DKK1可能为胰腺管道腺癌 (PDAC) 提供新的治疗策略.

关键词:
蜂聊天 蜂聊天 蜂聊天DKK1 DKK1 的意思在WGCNA中,WGCNA是WGCNA.皮质内皮质的沟通胰腺管道腺癌瘤一个单细胞RNA-seqq.空间转录学 空间转录学瘤微环境是一个微环境.

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The Tumor Microenvironment02:17

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...