基因多态性和个人间的变异性,以应对抵抗训练
Chen Yang1,2, Yanchun Li3,4,5
1College of Physical Education, Shihezi University, Shihezi 832003, China.
Genes
|February 27, 2026
概括
维生素D受体 (VDR) 基因变异会影响个体对抗力训练的反应,在两性之间影响肌肉和骨的增加. 这些VDR基因多态可能引导个性化的培训计划.
科学领域:
- 遗传学 是一个遗传学.
- 运动生理学 运动生理学
- 运动科学 运动科学 运动科学
背景情况:
- 维生素D受体 (VDR) 基因多态性与肌肉和骨健康有关.
- 它们对抵抗训练适应能力的个体差异的影响,特别是性别之间的影响,仍然不清楚.
研究的目的:
- 研究VDR基因多态化与健康中国成年人抵抗训练的适应之间的关联.
- 探索基于VDR基因型的抵抗训练的性别特异反应.
主要方法:
- 191名健康的中国汉族成年人 (94名男性,97名女性) 接受了为期12周的抵抗训练计划.
- 评估包括力量,功率,身体组成和训练前后的肌肉形态.
- 参与者被基因定型为VDR多态:rs731236 (TaqI),rs7975232 (ApaI),rs1544410 (BsmI) 和rs2228570 (FokI).
主要成果:
- 抵抗训练显著改善了多个健身指标.
- VDR基因型rs731236 (AG) 和rs1544410 (CT) 与较大的骨矿物质含量增加有关.
- 性别特定的发现:在女性中,rs731236-AA与力量/功率的增加相关,而AG基因型改善了身体组成. 在男性中,rs1544410-CC与较大的下肢肌肉生长有关.
结论:
- VDR基因多态性 (rs731236,rs1544410) 影响抵抗训练反应的个体变异性.
- 这些关联显示出不同的性别和表型特异性.
- 这些发现表明,基因型信息的个性化抗性训练策略有潜力.
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