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Updated: Feb 28, 2026

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父亲UBE3A的RNAi诱导的表达方式

Hye Ri Kang1, Violeta Zaric2, Volodymyr Rybalchenko2

  • 1Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX 75390, USA.

Genes
|February 27, 2026
PubMed
概括

通过RNA干扰准SNORD115有效地在神经元中重新激活了父亲的UBE3A表达. 这项研究表明,通过恢复老鼠和人类细胞中的基因功能,对安吉尔曼综合征有很大的希望.

关键词:
安吉尔曼综合征是什么意思它们是RNAiRNAi.这就是UBE3A.在UBE3A-ATS中使用.这是一个shRNARNA.

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