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Updated: Feb 28, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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新型细胞毒性Pt(IV) 化合物具有改善的安全性

Anastasia A Antonets1, Ksenia M Voroshilkina1, Ilya A Shutkov1

  • 1Department of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow 119991, Russia.

International journal of molecular sciences
|February 27, 2026
PubMed
概括

新的 (IV) 复合物与维生素E类似物显示出增强的抗氧化和抗癌活性. 这些新型化合物显示出对癌细胞的有效性提高,同时减少对正常细胞的毒性,为癌症治疗提供了一个有前途的策略.

关键词:
它具有抗癌活性,具有抗癌活性.抗氧化剂活性 抗氧化剂活性西斯普拉丁 (cisplatin) 是一种制剂.结合方式 结合方式细胞毒性 细胞毒性氧化烯酸是氧化烯酸的重要组成部分.金 (IV) 的使用.

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