GenReP:TP53

Austin Spadaro1, Alok Sharma2,3,4, Iman Dehzangi1,5,6

  • 1Center for Computational and Integrative Biology, Rutgers University, Camden, NJ 08102, USA.

PubMed
概括

这项研究引入了一种新的机器学习模型,用于预测药物如何影响TP53瘤抑制基因. 该工具通过理解基因表达变化,有助于开发新的癌症疗法.

相关概念视频

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Pharmacodynamic Models: Direct Effect Model and Indirect Response Model01:29

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Pharmacodynamic Models: Additive and Proportional Drug Effect Model01:09

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Pharmacodynamic Models: Emax Drug–Concentration Effect Model01:18

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Physiological Pharmacokinetic Models: Assumption with Protein Binding01:13

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