晚期外周动脉疾病患者的并发性静脉疾病:患者和肢体水平分析
Daniela Marinescu1, Laurențiu Augustus Barbu2, Tiberiu Stefăniță Țenea Cojan2
1Department of Surgery, Emergency County Hospital, University of Medicine and Pharmacy of Craiova, 2 Petru Rares Street, 200349 Craiova, Romania.
Life (Basel, Switzerland)
|February 27, 2026
概括
在晚期外围动脉疾病 (PAD) 中,静脉功能障碍是常见的,与动脉严重程度有关. 识别这种动脉-静脉联系可能会改善对肢体威胁性缺血的治疗.
科学领域:
- 血管外科 血管外科
- 心脏病学 心脏病学
- 血管学 血管学
背景情况:
- 先进的外周动脉疾病 (PAD),特别是慢性肢体威胁性缺血,导致肢体不良结果和高截肢风险.
- 传统的PAD评估侧重于动脉阻塞,往往忽视了同时存在的静脉功能障碍.
- 静脉功能障碍在PAD病理生理学中的作用在临床实践中未得到充分承认.
研究的目的:
- 调查晚期PAD患者静脉疾病的患病率.
- 评估静脉疾病,动脉严重性标志物和临床结果之间的关联.
- 为了确定静脉功能障碍是否是肢体威胁性缺血的一个组成部分.
主要方法:
- 在五年内对241名患有晚期PAD的患者进行了回顾性队列分析.
- 静脉疾病通过成像定义,有深静脉血栓形成史和.
- 通过多式成像评估动脉严重程度;在患者和四肢层面进行分析.
主要成果:
- 在68.9%的患者中发现并发性静脉疾病,主要是单边的.
- 静脉疾病与严重的动脉标志物相关:流入性疾病,高闭塞得分,小腿流量差,缺少踏板门.
- 静脉疾病患者的未调整大截肢率较低.
结论:
- 同时的静脉疾病在晚期PAD中非常普遍,并且与动脉严重程度有关.
- 静脉功能障碍是肢体威胁性缺血的一个组成部分,而不仅仅是伴随性疾病.
- 综合静脉评估可以提高对高级PAD的理解和管理.
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