多种可修改的风险因素对心血管疾病死亡率的累积影响
Jonathan Yunzhou Xiong1, Kai Goldenstein Vonkiel1, Lance Ridpath1
1Department of Clinical Sciences, West Virginia School of Osteopathic Medicine, 400 Lee Street, Lewisburg, WV 24901, USA.
Journal of clinical medicine
|February 27, 2026
概括
多种风险因素的累积影响在西弗吉尼亚州的县里显著增加了心血管疾病死亡率. 解决综合社会经济和医疗保健准入问题对于减少死亡至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 心血管疾病 (CVD) 仍然是导致死亡的主要原因.
- 了解累积风险因素对心脏病死亡率的影响对于有针对性的干预措施至关重要.
- 西弗吉尼亚州为研究社会经济和医疗保健准入因素对心血管疾病结果的相互作用提供了一个独特的环境.
研究的目的:
- 评估西弗吉尼亚州各县可修改风险因素的累积负担与心血管疾病死亡率之间的关联.
- 为了确定组合的风险因素是否对心脏病死亡率具有超出其个体贡献的协同效应.
主要方法:
- 追溯观察性研究分析了西弗吉尼亚州 (2011-2020) 县的心血管疾病死亡率和可修改的风险因素 (收入,PCP比率,食物沙漠状况).
- 数据来源于人口普查局,AMA,美国农业部和WV HHS.
- 使用多重线性回归和ANOVA分析风险因素与心血管疾病死亡率之间的关系.
主要成果:
- 综合风险因素与心血管疾病死亡率的关联比单个因素更强.
- 每个个别的风险因素 (收入,PCP比率,FDS) 都与心血管疾病死亡率有显著的关联.
- 在PCP比率和收入以及FDS和收入之间发现了显著的双向相互作用,表明了协同效应.
结论:
- 具有多个累积风险因素的县经历了不成比例地更高的心血管疾病死亡率.
- 风险因素对心脏病死亡率的综合影响超过了它们单个影响的总和.
- 在县级解决累积的社会经济和医疗保健准入因素对于减轻心血管疾病死亡率至关重要.
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