关于ACTIVE干预对有或没有轻度痴呆症的老年人和他们的护理伙伴的试点双臂交叉随机对照试验的协议
Oluwaseun Adeyemi1, Tracy Chippendale2, Joshua Chodosh3,4,5
1Department of Emergency Medicine, New York University Grossman School of Medicine, New York, NY 10016, USA.
Journal of clinical medicine
|February 27, 2026
概括
这项试点研究评估了ACTIVE干预措施,以改善老年人身体活动,包括那些患有阿尔茨海默病相关痴呆症 (AD/ADRD) 的老年人,为未来的试验显示了希望.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
背景情况:
- 老年人,特别是患有阿尔茨海默病和阿尔茨海默病相关痴呆症 (AD/ADRD) 的老年人,体验到身体活动减少,跌倒风险增加和生活质量下降.
- 活动跟踪,护理伙伴共同参与,文字提醒,教学教育,视频引导的身体康复和运动 (ACTIVE) 试验针对这个问题.
- 本试点研究评估了ACTIVE干预措施的可行性和初步有效性.
研究的目的:
- 评估ACTIVE干预措施的可行性和初步有效性,以提高老年人,包括患有AD/ADRD的老年人身体活动.
- 收集数据,为全面实施试验的设计提供信息.
主要方法:
- 一个双臂的,随机的,分析师盲目的交叉试点试验,涉及50个社区居住者 (老年成人护理合作伙伴).
- 参与者根据AD/ADRD诊断进行了分层,并随机选择接受ACTIVE干预 (活动跟踪,文本,练习,视频,康复) 或仅仅活动跟踪.
- 测量了可行性 (招聘,坚持,保留) 和初步有效性 (活动,跌倒风险,功能,生活质量),以及来自二次面试的定性数据.
主要成果:
- 该研究将产生有关ACTIVE干预可行性的数据,包括招聘,执法和保留率.
- 将收集有关体力活动指标,跌倒风险,功能限制和生活质量的初步疗效数据.
- 将获得对参与者体验,促进者和阻碍体育活动参与的障碍的定性见解.
结论:
- 这项试点研究对于确定ACTIVE干预措施的可行性和初步有效性至关重要.
- 结果将指导对AD/ADRD或没有ADRD的老年人进行ACTIVE试验的完善和全面实施.
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