代谢功能障碍相关的肥胖性肝病和肉症:文献综述
Hiroki Nishikawa1, Soo Ki Kim2, Sachiyo Yoshio3
1Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Takatsuki 569-8686, Osaka, Japan.
Journal of clinical medicine
|February 27, 2026
概括
与代谢功能障碍相关的肥胖性肝病 (MASLD) 和肉病有着复杂的双向关系. 本综述探讨了它们之间的联系,强调了肝纤维化,胰岛素抵抗和肌肉健康在MASLD患者中如何交织在一起.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 代谢障碍 代谢障碍 代谢障碍
- 老年病的医生 老年病的医生
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 是一种新的术语,用于与代谢问题相关的肝病.
- 标志着肌肉质量和力量下降的萨科佩尼亚,在老年人口和慢性肝病中越来越多地被识别出来.
- 胰岛素耐药性 (IR) 影响骨肌肉,这是葡萄糖处置的主要部位,是MASLD和肉症的关键因素.
研究的目的:
- 审查目前对MASLD和肉类症之间的关系的理解.
- 阐明肝病与肌肉健康之间的双向相互作用.
- 总结一下麻症,肌肉脂肪退化,肝纤维化和MASLD中的IR之间的相关性.
主要方法:
- 关于MASLD和肉类的当前研究的文献综述.
- 分析代谢异常对肝脏和肌肉健康的影响.
- 检查胰岛素抵抗和肝纤维化在疾病进展中的作用.
主要成果:
- 在麻症,肌肉脂肪退化,肝纤维化和MASLD中的IR之间存在强烈的相关性.
- MASLD和肉症表现出双向关系,创造了一个有害的循环.
- 由于营养和代谢障碍,慢性肝病患者的二次肉类是令人担忧的.
结论:
- MASLD和肉类是相互关联的,通过代谢和营养途径相互影响.
- 了解这种关系对于管理患有MASLD的患者和预防不良结果至关重要.
- 需要进一步的研究来探索针对这两种疾病的治疗策略.
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