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在外周动脉疾病中再血管化后使用高光谱成像进行实时输血评估

Michaela Kluckner¹, Wolfgang Hitzl^2,3,4, Florian K Enzmann¹

¹Department of Vascular Surgery, Medical University Innsbruck, 6020 Innsbruck, Austria.

Journal of clinical medicine

|February 27, 2026

概括

超光谱成像 (HSI) 显示在再血管化后微循环 (StO2,NIR) 得到改善,但结果与皮肤过渡氧气压 (TcPO2) 或临床结果无关,质疑HSI.

科学领域:

血管外科血管外科
医疗成像医学成像
生物医学工程生物医学工程

背景情况:

外周动脉疾病 (PAD) 的管理需要有效的组织 perfusion 评估.
超光谱成像 (HSI) 提供非侵入性输液评估,但缺乏与标准方法的验证.
现有的HSI研究通常使用小队列或单个测量,限制了临床适用性.

研究的目的:

在PAD患者的再血管化后,使用HSI和皮肤过渡氧气压 (TcPO2) 来前性评估组织输液的变化.
将HSI参数 (StO2,NIR,THI) 与TcPO2测量进行比较.
为了将HSI和TcPO2的发现与复血管化后的临床改善相关联.

主要方法:

一项前性队列研究,涉及Rutherford类别3-6 PAD的患者.
组织输液通过HSI和TcPO2评估,在重血管化前一天和再血管化后1-3天.
对HSI参数,TcPO2和临床改善之间的相关性分析.

主要成果:

通过HSI观察到STO2 (+12%) 和NIR (+9%) 的显著改善,以及TcPO2 (+16.2 mmHg).
通过HSI检测的组织血红蛋白指数 (THI) 没有显著变化.
在HSI参数和TcPO2或临床结果之间没有发现相关性;一些HSI测量显示,尽管成功进行了再血管化,但情况恶化.

结论:

虽然StO2,NIR和TcPO2在重血管化后有所改善,但HSI参数与TcPO2或临床结果没有相关性.
在HSI发现和既定措施 (TcPO2,临床状态) 之间存在显著差异,这引发了对HSI的有效性和评估术后输液的临床相关性的担忧.
该研究质疑基于TIVITA®的HSI对评估PAD重血管化结果的有用性.

关键词:

超光谱成像技术的使用.微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 微 perfusion 周围动脉疾病周围动脉疾病量化量化量化量化量化量化量化量化量化量化量化量化量通过皮肤进行氧气压力测量.

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