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一个微流体平台用于测试工程和生物医学应用中非牛顿流体的粘度

Yii-Nuoh Chang¹, Da-Jeng Yao^1,2

¹Institute of NanoEngineering and MicroSystems, National Tsing Hua University, Hsinchu 300, Taiwan.

|February 27, 2026

概括

本研究引入了一种微流体装置,用于测量高达50cP的非牛顿流体粘度. 增强的平台使用流量稳定器,用于各种应用中的高精度,低体积类风湿学.

科学领域:

流体动力学流体动力学
材料科学材料科学材料科学
生物医学工程生物医学工程

背景情况:

微流体设备为粘度测量提供精确的流体处理.
传统方法在广泛的粘度范围内测量非牛顿流体时面临局限性.
扩大可测量的粘度范围对于食品科学和生物医学诊断中的应用至关重要.

研究的目的:

开发和验证用于非牛顿式流体粘度传感的微流体平台.
将可测量的粘度范围从1-10cP扩展到1-50cP.
集成高流速流场稳定器,以提高高流速时的精度.

主要方法:

利用基于通道占用率的双相层流原理来确定相对粘度.
使用计算流体动力学 (CFD) 模拟来设计和优化流动稳定器.
使用模拟的血液和乳制品样本验证了微流体系统,并将结果与传统粘度计进行比较.

主要成果:

在高流量模拟中,优化的N5流稳定器设计将速度分布不对称性降低了50%以上.
微流体平台实现了超过95%的粘度准确度,样本体积误差低于5%.
成功监测了牛奶酸化和凝过程中的粘度变化,与标准测量结果有很好的一致性.

结论:

开发的微流体平台显著提高了非牛顿流体的风力测量能力.
集成的流量稳定器使得高精度粘度测量在一个扩展范围 (1-50 cP).
这项技术在食品工程,生物医学诊断和工业流体监测等领域具有很大的应用潜力.

关键词:

乳制品凝乳制品凝这是一个微流体芯片.非牛顿流体的流体.粘度测量测量的粘度测量

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