在非腹性小麦敏感性中Atopy和其他敏感性:是否有相关的过敏背景? † † † †† † † †† † † † † † † † †
Aurelio Seidita1,2,3, Pasquale Mansueto2, Mirco Pistone1,2
1Unit of Internal Medicine, "V. Cervello" Hospital, Ospedali Riuniti "Villa Sofia-Cervello", Via Trabucco, 180, 90146 Palermo, Italy.
Nutrients
|February 27, 2026
概括
患有非乳性小麦敏感症 (NCWS) 的患者表现出较高的亚托皮性疾病,多种食物敏感性和自我报告的牛奶不耐受性. 这些过敏性可能有助于诊断NCWS并将其与功能性胃肠道疾病区分开来.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
- 过敏 过敏是一种过敏.
背景情况:
- 非乳性小麦敏感性 (NCWS) 可能与过敏反应有关.
- 以前的研究表明,NCWS患者的亚托皮性疾病发病率较高.
研究的目的:
- 确定NCWS患者中阿托皮性疾病和其他过敏症的患病率和特征.
- 为了确定NCWS诊断的潜在过敏标志物.
主要方法:
- 在饮食干预之前,对NCWS患者的临床,实验室和组织学数据的回顾性分析.
- 将NCWS患者与被诊断患有乳病 (CeD) 或易怒肠综合征/功能性消化不良 (IBS/FD) 的对照组进行比较.
主要成果:
- 与CeD (19.3%) 和IBS/FD (21.5%) 组相比,NCWS患者的亚托皮性疾病患病率显著更高 (32.8%).
- 在NCWS受试者和对照者中,多重食物敏感性 (MFSs) (39.8%) 和自我报告的牛奶不耐受性 (SRMI) (65.9%) 的频率更高.
- 通过逻辑回归确定了亚托皮性疾病,MFS和SRMI作为与NCWS诊断相关的显著变量.
结论:
- 与CeD和IBS/FD患者相比,NCWS患者的阿托皮性疾病,MFS和SRMI的发生率增加.
- 这些过敏性可能代表NCWS中更广泛的过敏性概况.
- 识别这些条件可以帮助NCWS从功能性胃肠道疾病的差异诊断.
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