急性L-氨酸补充剂和冲刺运动在超重者中引起明显的食欲和炎症反应:一个随机,平衡和交叉设计研究
Elias de França1,2, Ronaldo Vagner Thomatieli-Santos1,3, Rita de Cássia Aquino2
1Interdisciplinary Graduate Program in Health Sciences, Universidade Federal de São Paulo, São Paulo 04024-001, SP, Brazil.
Nutrients
|February 27, 2026
概括
高强度冲刺运动和L-氨酸补充剂影响食欲调节的神经和超重男性的炎症. 冲刺运动降低了食欲,而单独的L-氨酸降低了主观的食欲感知.
科学领域:
- 运动生理学 运动生理学
- 营养生物化学 营养生物化学
- 调节食欲 调节食欲是什么意思
背景情况:
- 超重的人经常经历食欲调节的改变.
- 补充L-氨酸和高强度运动是控制食欲的神经和炎症标志物的潜在调节剂.
- 了解运动,L-氨酸和食欲激素之间的相互作用对于管理体重和代谢健康至关重要.
研究的目的:
- 研究L-氨酸补充剂与高强度冲刺运动相结合对控制食欲的神经的急性影响.
- 评估对主观感知食欲 (SPA) 和腹 (SPS),食物摄入量和超重成人炎症反应的影响.
- 探索神经和细胞因子变化与主观食欲和食物摄入之间的关联.
主要方法:
- 一个双面罩的,随机的,平衡的,交叉设计,涉及12个久坐的超重男性.
- 四个实验条件:使用L-氨酸 (EX-Leu) 进行运动,使用安慰剂 (EX-PLA) 进行运动,使用L-氨酸 (SED-Leu) 进行静止活动,使用安慰剂 (SED-PLA) 进行静止活动.
- 测量包括食物摄入量,SPA,SPS,神经 (GLP-1,PYY,CCK,格林) 和细胞因子 (IL1-β,IL-6,IL-10,TNF-α) 在急性冲刺运动和L-白/安慰剂补充后.
主要成果:
- 与没有运动 (SED-PLA) 的安慰剂相比,运动 (EX-PLA,EX-Leu) 和L-素 (SED-Leu) 都降低了主观食欲感知 (SPA).
- 与安慰剂 (EX-PLA) 进行的冲刺运动改善了主观腹感 (SPS),而这两种运动条件 (EX-PLA,EX-Leu) 减少了食物摄入量.
- 与运动一起补充L-氨酸诱导了促炎反应 (增加IL-6,IL1-β),而单独运动显示了抗炎特征.
结论:
- 冲刺运动表现出一致的急性厌食效应,减少了超重男性的食欲和食物摄入量.
- 补充L-氨酸,特别是与运动相结合时,似乎会影响炎症平衡,可能有助于控制食欲.
- 氨酸对和食物摄入的独立影响需要进一步研究,强调运动,营养和食欲调节之间的复杂相互作用.
更多相关视频
06:13Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
Published on: December 1, 2023
1.8K
07:26Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
21.5K
相关概念视频
Regulation of Food Intake
3.0K
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
3.0K
Muscle Recovery and Fatigue
4.5K
Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
4.5K
