探索饮料摄入量和饮食时间模式在药物诱导的 Xerostomia:一个横截面试点研究
Alhanoof K Alarfaj1, Abdul B Barmak2, Waldir M Filho1
1Department of General Dentistry, Eastman Institute for Oral Health, University of Rochester, Rochester, NY 14620, USA.
药物诱导的口腔干燥 (xerostomia) 与晚餐时间有关,而不仅仅是液体摄入. 这表明人们如何管理因药物而导致的口腔干燥的行为变化.
科学领域:
- 口腔医学是指口腔医学.
- 药理学 药理学是指药理学的学科.
- 饮食科学 饮食科学
背景情况:
- Xerostomia (口腔干燥) 是一种常见的药物副作用,影响口腔功能.
- 有限的研究探讨了异口症对中年成人饮料摄入量和饮食时间的影响.
- 这项研究侧重于非癌症人群中药物诱导的异口症.
研究的目的:
- 为了研究饮料摄入量,饮食时间和唾液腺功能之间的关系,在药物诱导的异口症患者中.
- 评估唾液腺功能的主观和客观指标.
- 了解对口腔干燥的行为适应.
主要方法:
- 对90名使用抗胆固醇药物的成年人 (45-66岁) 进行横截面试验研究.
- 评估唾液功能:未刺激的全唾液 (UWS),小唾液流 (MSF) 和 Xerostomia 库存 (XI).
- 使用了关于饮料摄入量和饮食时间的验证问卷;根据人口统计和并发性疾病进行了调整.
主要成果:
- 低度与较高的异口症严重程度 (XI分数) 和较大的抗胆固醇药物负担相关.
- 最后的食物/零食摄入的时间独立地与增加的异口症有关.
- 无论是总饮料量还是摄入水量的量都与唾液流量或异口症得分无关.
- 夜间的饮食与更高的抗胆固醇负担有关.
结论:
- 食和零食的时间,而不是液体体积,可能更好地表明药物诱导的异口症的症状负担.
- 个人根据口腔干燥而调整他们的饮食行为.
- 研究结果强调了考虑摄入时间在管理口症时的重要性.
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