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Updated: Feb 28, 2026

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
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在实验室中对Poly ((D,L-lactide-co-glycolide) In Situ凝的评估以及在小鼠皮下注射后的药理动力学,用于模型药物

Sandy Van Hemelryck1, Charlotte Vercammen1,2, Eline Seldeslachts1,2

  • 1Clinical Pharmacology and Pharmacometrics, Johnson & Johnson, Turnhoutseweg 30, 2340 Beerse, Belgium.

Pharmaceutics
|February 27, 2026
PubMed
概括

这项研究表明药物特性和配方变量如何影响in vitro药物释放从in situ凝 (ISG) 长效注射剂 (LAI). 它还建立了一个 in vitro-in vivo 相对应 (IVIVC) 赛莱科西布ISGs,帮助LAI的发展.

关键词:
在现场的凝.在体外释放的 in vitro 释放.在体外体内相对应的相关性药物动力学 药物动力学溶解度 溶解度 溶解度 溶解度持续释放 持续释放 持续释放

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