电极尖端与左心室导电系统之间的距离在左束分支区域加速时
Fan Zhang1, Wei Ma1, Shaobo Fan1
1Chest Hospital, Tianjin University, Tianjin, China.
Journal of cardiovascular electrophysiology
|February 27, 2026
概括
左捆分支区域节奏 (LBBAP) 在电极尖距离左心室导电系统 (LVCS) 距离2mm以内时实现导电系统 (CS) 捕获. 这种精确的位置优化了步调参数,并减少了QRS持续时间.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 心脏节拍是因为心脏节拍.
背景情况:
- 左捆分支区域节奏 (LBBAP) 是一种生理节奏技术.
- 即使没有可检测的CS潜力,也可以实现导电系统 (CS) 的捕获.
- 精确的电极放置对于有效的LBBAP至关重要.
研究的目的:
- 在LBBAP过程中测量电极尖端和左心室导电系统 (LVCS) 之间的距离.
- 为了评估电极-LVCS距离对节奏参数的影响.
- 为了确定成功的CS捕获的最佳距离.
主要方法:
- 16只狗被分为传导系统节奏 (CSP) 和左心室隔膜节奏 (LVSP) 组.
- 一个3D电解剖绘图 (EAM) 系统可视化了LVCS和引导电极植入.
- 病理样本测量了电极尖端到LVCS的距离,植入深度和角度.
主要成果:
- 该CSP组 (包括LBBAP和左带节奏) 显示电极尖端到LVCS距离≤2mm.
- 在刺激到左心室激活时间 (Stim-LVAT),Stim-Retro-His间隔和QRS持续时间之间观察到显著的差异.
- CSP组表现出较短的Stim-LVAT (48.75 ± 2.38 ms与59.75 ± 2.05 ms相比) 和QRS持续时间 (89.50 ± 4.34 ms与109.88 ± 5.96 ms相比).
结论:
- 当电极尖端到LVCS的距离为≤2mm时,可以成功捕获CS.
- 在这样的距离下,在≤1.5V/0.5ms的节奏输出时发生了最佳捕获.
- 本研究量化了有效的LBBAP和CS捕获的临界距离.
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