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Updated: Feb 28, 2026

Aip1p Dynamics Are Altered by the R256H Mutation in Actin
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在酸化后的α-actinin-2actin结合域的形形态动力学

Helene Tigro1, Matthew C Childers2, Michael Regnier2

  • 1Department of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, Florida, United States of America.

Biophysical journal
|February 27, 2026
PubMed
概括

心脏α-actinin-2的酸化改变了其活性蛋白结合域结构,促进了与F-actin的相互作用. 这种机制有助于在机械应力下稳定瘤,这对心肌适应至关重要.

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