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Updated: Feb 28, 2026

Expression of Recombinant Proteins in the Methylotrophic Yeast Pichia pastoris
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Expression of Recombinant Proteins in the Methylotrophic Yeast Pichia pastoris

Published on: February 25, 2010

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[分子伴侣会影响Pichia pastoris中单域抗体的表达]

Weiming Su1,2, Ye Qin3, Haiwei Zhang2

  • 1Wuhan Institute of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan 430056, Hubei, China.

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
|February 27, 2026
PubMed
概括

在Pichia pastoris中与单域抗体 (sdAbs) 共同表达的分子伴侣增强了sdAb的产生和稳定性. 像Sec,BZIP和YPDI这样的特定伴奏物改善了表达,热稳定性和抗变性,为优化sdAb制造提供了洞察力.

关键词:
这就是Pichia pastoris.分子陪伴者是一个分子陪伴者.物理和化学特性.二级结构是二级结构的二次结构.一个单域抗体的抗体.

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