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Updated: Feb 28, 2026

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells
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Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells

Published on: April 9, 2018

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P450 TxtE的时钟控制区域选择性使芳香化合物的精确位置功能化成为可能

Xin Yang1, Yue Pan1, Tingwei Miao1

  • 1Shanghai Engineering Research Center of Molecular Therapeutics & New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China.

JACS Au
|February 27, 2026
PubMed
概括

研究人员设计了一种细胞染色体P450酶,用于高选择性C6化l-三. 这种计算机辅助的设计克服了功能关闭的芳香部位的挑战.

关键词:
这就是C6功能化.时钟正在转动,时间在转动.计算机辅助的酶设计细胞染色体P450 TxtE TxtE 在理性的设计理性的设计.地区选择性化.

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