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Updated: Feb 28, 2026

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
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Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

Published on: June 7, 2018

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超越折叠酶:具有氧活性的"固体伴侣"释放可回收的,无HPLC氧化蛋白折叠

Shunpei Iwamoto1, Yuya Nishizawa1, Hayato Yokose2,3

  • 1Department of Chemistry, School of Science, Tokai University, 4-1-1 Kitakaname, Hiratsuka-Shi, Kanagawa 259-1292, Japan.

JACS Au
|February 27, 2026
PubMed
概括

研究人员开发了一种可重复使用的聚合物"固体伴侣",模仿蛋白质二硫化异合酶 (PDI) 进行高效的氧化蛋白折叠. 这种新型材料使得可回收,无酶的二硫化物键形成和蛋白质重新折叠成为可能,克服了当前方法的局限性.

关键词:
酶模型是酶模型.不同质的催化剂.材料科学 材料科学 材料科学蛋白质二硫化异硫酶酶是什么蛋白质折叠 蛋白质的折叠是一种.可持续的化学 可持续的化学

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