在ISS上6个月期间和6个月后评估左心室收缩性,使用斑点追踪模式
Philippe Arbeille1, Kathryn Zuj1, Nicole Vincent2
1UMPS-CERCOM. Medical School University of Tours, Tours, France.
Frontiers in physiology
|February 27, 2026
概括
宇航员的心脏收缩率在太空飞行期间略有下降,通过斑点跟踪测量. 在返回地球后,功能很快恢复正常,这表明适应而不是持久的损伤.
科学领域:
- 心血管生理学心血管生理学
- 太空医学 太空医学
- 生物医学工程 生物医学工程
背景情况:
- 评估心脏收缩性对于了解心血管健康至关重要.
- 斑点跟踪回声心脏学提供了一种非侵入性方法来评估心肌运动.
- 太空飞行给心血管系统带来了独特的生理挑战.
研究的目的:
- 为了评估宇航员使用斑点跟踪的心脏收缩性.
- 在长时间太空飞行之前,期间和之后评估心脏功能的变化.
- 为了研究太空飞行对心肌运动的影响.
主要方法:
- 十名宇航员接受了左心室顶视图的斑点跟踪分析.
- 测量是在飞行前 (PRE),飞行第150天 (FD150),飞行后4天 (R4) 进行的.
- 关键参数包括平均斑点移位,移位和斑点数的乘积,以及最大移位面积.
主要成果:
- 在太空飞行期间观察到减少平均斑点位移的趋势 (p=0.052).
- 斑点位移和计数的乘积是相对于R4 (p=0.021) 的显著较低的入空量.
- 与飞行前相比,在太空飞行期间最大位移的面积显著减少 (p=0.017).
结论:
- 太空飞行与心脏收缩能力的轻微减少有关.
- 所有测量的参数都通过R4恢复到飞行前的水平.
- 观察到的变化可能与减少的体力活动或血量有关,而不是心肌重塑.
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