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Updated: Feb 28, 2026

Chemical Modification of the Tryptophan Residue in a Recombinant Ca2+-ATPase N-domain for Studying Tryptophan-ANS FRET
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Chemical Modification of the Tryptophan Residue in a Recombinant Ca2+-ATPase N-domain for Studying Tryptophan-ANS FRET

Published on: October 9, 2021

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类似FNR的单元与C端相关的残留物相互作用,触发nNOS降解酶域的结构灵活性变化

Yubo Wang1,2, Nan Wang1,2

  • 1Research Center for Biochemistry and Molecular Biology, Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Xuzhou, Jiangsu, China.

Frontiers in neuroscience
|February 27, 2026
PubMed
概括

神经性氧化合成酶 (nNOS) 抑制剂由于对其还原酶域动态的理解不足,其有效性有限. 这项研究揭示了稳定辅因子的关键残留物,为改善神经疾病中的nNOS抑制剂提供了新的标.

关键词:
这就是FAD FAD.FMN FMN FMN 的意思是什么?这是一个类似FNR的单元.在NADP (H) 中,分子动态模拟分子动态模拟nNOS还原酶域的域名为nNOS.

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