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在三个美国队列研究中,饮食质量与口腔微生物群之间的关联
Fangyu Li1, Samuel Anyaso-Samuel1, Yukiko Yano1
1Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Journal of oral microbiology
|February 27, 2026
概括
饮食质量影响口腔微生物群的多样性,特别是添加糖的摄入量. 高额添加糖消费与口腔微生物多样性和特定细菌种群的减少有关.
科学领域:
- 微生物组研究的研究.
- 饮食科学 饮食科学
- 人类健康 人类健康 人类健康
背景情况:
- 口腔微生物群对整体健康起着重要作用.
- 饮食习惯对口腔微生物组成的影响尚未完全理解.
研究的目的:
- 通过2015年健康饮食指数 (HEI) 评估饮食质量与口腔微生物组之间的关联.
- 分析了来自三个大型队列研究的5546名参与者的数据.
主要方法:
- 饮食质量从FFQ数据中得分,并归纳为HEI组件.
- 估计了α和β多样性,以及属级微生物的存在和丰度.
- 用调整为混因素的回归模型对队列特定估计的元分析.
主要成果:
- 年龄,吸烟,教育,以及添加糖的HEI成分解释了β多样性的变化.
- 整体饮食质量与α多样性没有相关性,但添加糖摄入量显示出相反的关联.
- 大多数属级的关联与添加糖消费有关.
结论:
- 添加糖的消费一直与口腔微生物多样性有关.
- 特定的口腔微生物属也与添加糖的摄入量有关.
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