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在儿童中,与Serratia Marcescens相关的血液感染

Memduha Sari¹, Mustafa Genceli², Ozge Metin Akcan²

¹Antalya Education and Research Hospital, Department of Pediatric Gastroenterology, Antalya, Turkey.

Sudanese journal of paediatrics

|February 27, 2026

概括

在儿童中,Serratia marcescens bacteremia导致高死亡率,并涉及抗菌素耐药性. 及时识别和量身定制的经验治疗对于改善儿科重症监护机构的结果至关重要.

科学领域:

儿童传染病儿童传染病
临床微生物学临床微生物学
医院流行病学医院流行病学

背景情况:

塞拉蒂亚马尔塞森斯是病房感染的重要原因,特别是在脆弱的儿科群体中.
儿科S. marcescens bacteremia由于不断演变的抗菌素耐药性模式,提出了独特的挑战.

研究的目的:

调查儿科S. marcescens bacteremia的临床特征,抗菌素耐药性概况和死亡率预测因素.
为儿童S. marcescens感染的临床管理策略提供信息.

主要方法:

从2017年1月至2021年12月,对77名患有S. marcescens细菌病的儿科患者 (0-18岁) 的回顾性分析.
评估人口统计,并发症,抗菌素敏感性测试,治疗方案和死亡结果.

主要成果:

总死亡率为31.2%,早产和慢性疾病是显著的风险因素.
对于美罗 (50%) 和皮佩拉西林-塔扎巴克坦 (38.9%) 观察到高耐药率,而阿米卡辛的耐药性较低 (2.5%).
多种药物耐药性普遍存在,需要频繁修改经验性抗生素疗法.

结论:

儿科S. marcescens细菌病与大量的死亡率和令人担忧的抗菌素耐药性有关.
优化经验性治疗选择和管理潜在的风险因素对于改善患者的治疗结果至关重要.

关键词:

细菌病是什么意思细菌病是什么意思多种药物耐药性多种药物耐药性没有共生关系的.塞拉蒂亚 (Serratia marcescensens) 是一种的植物.

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