术后患者报告的结果与部功能表现在退行性宫骨髓病的相关性
Harshit Arora1, Hassan Darabi1, Vishwajeet Singh1
1Department of Neurosurgery, University of Kentucky College of Medicine, Lexington, KY, United States.
North American Spine Society journal
|February 27, 2026
概括
退行性宫肌病 (DCM) 患者在手术后显示出改善的生活质量,上肢功能更好与自我报告的结果相关. 本研究为DCM-72得分确定了临床重要差异 (MCID) 的最小值,以帮助评估恢复.
科学领域:
- 脊髓外科手术 脊髓外科手术
- 神经学 神经学
- 整形外科 整形外科 整形外科
背景情况:
- 退行性宫髓病 (DCM) 是由慢性宫脊髓压缩引起的,导致上肢功能障碍,失衡和膀问题.
- 患者报告的结果指标 (PROMs),如mJOA,Nurick,NDI和DCM-72,用于疾病分层.
- 需要在DCM中将主观患者报告与客观功能评估相关联.
研究的目的:
- 评估DCM患者的自我报告措施和客观上肢评估之间的临床相关性.
- 在患有DCM的个体中推导DCM-72问卷的临床重要差异最小值 (MCID).
主要方法:
- 一项前性,两中心的研究包括99名DCM患者和34名对照,在手术前和手术后6个月和12个月评估.
- 进行了全面的上肢评估 (灵巧度,感觉,力量) 和PROMs.
- 统计分析检查了PROM进展和与功能评估的相关性,p < .05被认为是显著的.
主要成果:
- 在术后的mJOA,NDI,Nurick和PROMIS-10物理分数中观察到显著的改善.
- 上肢功能指标与自我报告的结果有很强的相关性,表明生活质量有所改善.
- 使用mJOA作为,DCM-72的MCID值在6个月后大约为1.44 (轻度),3.20 (中度) 和6.92 (严重).
结论:
- DCM患者在自我报告的结果中经历了显著的术后益处,与改善的上肢功能密切相关.
- 导出DCM-72 MCID值为评估DCM治疗后功能恢复提供了临床上有意义的基准.
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