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Updated: Feb 28, 2026

Adult Mouse Venous Hypertension Model: Common Carotid Artery to External Jugular Vein Anastomosis.
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血管不稳定和危细胞脱离是由转基因小鼠中的hIAPP聚合介导的

J Koepke, L Mateus Gonçalves, C Andrade Barboza

    bioRxiv : the preprint server for biology
    |February 27, 2026
    PubMed
    概括

    在2型糖尿病 (T2D) 中的人类小岛氨基酸多 (hIAPP) 沉积会破坏小岛微血管的稳定性. hIAPP聚合会导致内皮细胞功能障碍和细胞膜脱离,损害血管功能,并可能恶化T2D.

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