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Updated: Feb 28, 2026

Transgenic Rodent Assay for Quantifying Male Germ Cell Mutant Frequency
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以动机为中心的分析揭示了在人体中运行的通用和组织特异性突变机制

Safia Mahabub Sauty, Yun-Chung Hsiao, Leszek J Klimczak

    bioRxiv : the preprint server for biology
    |February 27, 2026
    PubMed
    概括

    身体突变发生在正常人体细胞中,时钟式的去胺和环氧化物暴露有助于组织间的突变发生. 紫外线辐射会改变皮肤,而APOBEC酶会影响膀和肺等器官.

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