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Updated: Feb 28, 2026

Assessing Cell Cycle Progression of Neural Stem and Progenitor Cells in the Mouse Developing Brain after Genotoxic Stress
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神经细胞循环重新进入通过ALS中复制依赖DNA损伤定义了不同的结果

Jonathan Plessis-Belair, Roger B Sher

    bioRxiv : the preprint server for biology
    |February 27, 2026
    PubMed
    概括

    细胞循环失调驱动神经退行性疾病中的神经元损失. 损坏的核运输触发了细胞循环的重新进入,导致ALS中的运动神经元退化,但CDK4/6抑制提供了保护.

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