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Updated: Feb 28, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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Published on: February 20, 2018

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发现和动态药理学的μ-阿片类受体阳性全osteric调节器

Evan S O'Brien, Junzheng Wang, Parthasaradhireddy Tanguturi

    bioRxiv : the preprint server for biology
    |February 27, 2026
    PubMed
    概括

    研究人员发现了针对μ-阿片类受体 (μOR) 的新型阳性全调节剂 (PAMs). 这些化合物为传统阿片类药物提供了潜在的替代品,旨在减少成和呼吸系统抑郁等副作用.

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