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Updated: Feb 28, 2026

Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging
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缺陷的BRCA1介导的DNA末端切除驱动着协同重复的形成和合成杀伤性

Namrata M Nilavar, Alberto Marin-Gonzalez, Francesca Menghi

    bioRxiv : the preprint server for biology
    |February 27, 2026
    PubMed
    概括

    与BRCA1相关的癌症具有由DNA修复缺陷驱动的协同重复 (TDs). BRCA1卷曲线突变抑制TDs,表明与同源重组分开的独特瘤发生途径.

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