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Updated: Feb 28, 2026

Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation
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Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation

Published on: August 21, 2017

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在调解MR1贩运和抗原呈现方面,SNAP23和SNAP25的作用相反

Se-Jin Kim, Corinna A Kulicke, David M Lewinsohn

    bioRxiv : the preprint server for biology
    |February 27, 2026
    PubMed
    概括

    突触相关蛋白23 (SNAP23) 增强了MR1抗原的呈现,而SNAP25则抑制了它. 这揭示了SNAP蛋白在MR1贩运和微生物感染期间MAIT细胞激活中的对立作用.

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