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Updated: Feb 28, 2026

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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SMARCAL1是ALT阳性瘤的候选治疗标

Angelo Taglialatela, Jina Lee, Benura Azeroglu

    bioRxiv : the preprint server for biology
    |February 27, 2026
    PubMed
    概括

    替代性端粒延长 (ALT) 对骨髓瘤至关重要. 研究人员发现,SMARCAL1对ALT阳性瘤至关重要,为这些侵袭性癌症提供了一个新的治疗标.

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