中年骨折的流行病学:来自英国生物库的自我报告和医院病例数据
Catherine Rolls1,2,3, Helen Dawes4, Marcus Munafo5
1Translational and Applied Research Group, University of Bristol, United Kingdom.
概括
中年骨折风险经常被忽视. 女人 女人 女人 女人 女人
科学领域:
- 流行病学 流行病学
- 整形外科 整形外科 整形外科
- 公共卫生 公共卫生
背景情况:
- 中年 (35-65岁) 骨折风险是未被认可的.
- 这个年龄组的骨健康有长期影响.
- 目前的临床模型可能无法完全捕捉中年骨折风险.
研究的目的:
- 描述中年成人 (年龄35-65岁) 的骨折流行病学.
- 分析骨折发生率模式,按性别,骨部位和年龄分层.
- 为了确定性别特定的中年骨折风险轨迹.
主要方法:
- 利用英国生物库的数据进行了两个互补的分析.
- 对自我报告的骨折 (2006-2010年) 的横截面分析.
- 使用链接的医院情节统计 (HES) 数据进行纵向队列分析 (2001-2022).
主要成果:
- 骨折发生率因年龄和性别而异.
- 女性的风险从35岁开始增加,在40多岁中期加速.
- 男性在中年早期 (35-45岁) 经历了高峰风险,而女性的风险超过了男性在45岁左右的风险.
结论:
- 女性骨折风险从35岁开始上升,从45岁开始加速.
- 中年性别特定的骨折发病率轨迹与当前的临床模型有所不同.
- 需要进一步研究为预防中年骨折量身定制的风险评估.
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