从证据到实践:对CRS治疗的考虑
Diego M Conti1,2, Eduardo J Correa3, Rosario B Spuches4
1Escuela de Doctorado UAM, Centro de Estudio de Posgrado, Universidad Autónoma de Madrid, Madrid, Spain.
Acta oto-laryngologica
|February 27, 2026
概括
管理慢性鼻炎 (CRS) 需要平衡算法指导与临床专业知识. 以患者为中心的护理,解决并发病症,并确保遵守基本疗法是有效治疗的关键.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 过敏和免疫学 过敏和免疫学
- 药理学 药理学是指药理学的学科.
背景情况:
- 慢性鼻炎 (CRS) 显著影响生活质量.
- 在了解2型炎症和生物学的进步提供了新的治疗途径.
- 患者的异质性和并发症复杂化了CRS的算法管理.
研究的目的:
- 审查当前的CRS管理实践.
- 识别现有治疗方法的局限性.
- 在CRS中提出最佳的,以患者为中心的临床实践原则.
主要方法:
- 对当前的指导方针和临床研究进行叙述性审查.
- 核心主题的分析,包括皮质类固醇,手术,ATAD和生物制剂.
- 评估治疗算法和临床判断之间的平衡.
主要成果:
- 鼻腔内皮质类固醇和盐水灌是基础,但坚持通常很差.
- 透视鼻手术有好处,但在专业中心之外的结果各不相同.
- 生物药物对特定患者有希望,但成本和可访问性是障碍.
- 在脱敏后 (ATAD) 的阿司匹林治疗对于特定的表型仍然有价值.
- 过度依赖算法可能导致过度简化;临床专业知识和患者参与至关重要.
结论:
- 有效的CRS管理需要以患者为中心的护理,整合并发症.
- 坚持基本疗法和明智地使用先进干预措施是必不可少的.
- 将算法建议与专业判断相结合,可以确保有效,公平和可持续的CRS护理.
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