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Updated: Feb 28, 2026

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在TIMP2的N端域的化学合成总量

Yuanmei Sun1, Yuqi Zhang1, Chunmao He1

  • 1School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China. hecm@scut.edu.cn.

Organic & biomolecular chemistry
|February 27, 2026
PubMed
概括

研究人员合成了金属蛋白酶2 (N-TIMP2) 蛋白质的组织抑制剂的N端域. 这为研究N-TIMP2如何与矩阵金属蛋白酶14 (MMP14) 相互作用并抑制瘤细胞转移提供了一个新的工具.

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Sorting of outer membrane proteins:
Mitochondrial outer membrane proteins are of two types: the transmembrane, beta-barrel porins, and the membrane-anchored, alpha-helical proteins. Beta-barrel porin precursors are translocated by the TOM complex and inserted into the outer mitochondrial membrane by the SAM complex. In contrast,...
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Generally, polypeptides are unfolded by two distinct...
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