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Updated: Feb 28, 2026

Quantifying Cytoskeleton Dynamics Using Differential Dynamic Microscopy
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会议介绍:生物分子功能:在生物暗物质中寻找功能的方法和基准

Jason E McDermott1, Yana Bromberg2, Hannah Carter3

  • 1Computational Biology Group, Pacific Northwest National Laboratory Richland, Washington 99352, USA2Department of Molecular Microbiology and Immunology, Oregon Health & Science University Portland, Oregon 97239, USA, Jason.McDemott@pnnl.gov.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
|February 27, 2026
PubMed
概括

计算生物学在确定分子功能的过程中面临着挑战. 新的AI / ML方法,包括几何蛋白质建模和序列设计的强化学习,为生物"暗物质"提供了创新的解决方案.

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Mechanical Protein Functions01:58

Mechanical Protein Functions

Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force. 
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Although black holes were theoretically postulated in the 1920s, they remained outside the domain of observational astronomy until the 1970s.
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