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Updated: Mar 1, 2026

Body Composition and Metabolic Caging Analysis in High Fat Fed Mice
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Body Composition and Metabolic Caging Analysis in High Fat Fed Mice

Published on: May 24, 2018

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与肥胖相关的MRAP2变体在MC4R和GHSR信号传输上的功能性特征

Alejandra V Rodríguez Rondón1,2, Karina Prins1,2, Femke Volker1,2

  • 1Obesity Centre CGG, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, the Netherlands.

Human molecular genetics
|February 27, 2026
PubMed
概括

黑色皮质素-2受体辅助蛋白-2 (MRAP2) 增强食欲调节受体信号传递,但与肥胖相关的变体在细胞模型中没有表现出功能影响,这表明当前测试方法的潜在良性或局限性.

关键词:
GPCR辅助蛋白质是一种辅助蛋白质.在 GPCR 信号中,GPCR 发出信号.在MRAP2的变体中.肥胖问题 肥胖问题

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