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在热冲击后,CPSF73激活和3'RNA聚合酶II暂停在读透转录期间丢失

Kaitlyn E Walsh1, James A Goodrich1, Jennifer F Kugel1

  • 1Department of Biochemistry, University of Colorado, Boulder, CO 80309, USA.

Cell reports
|February 27, 2026
PubMed
概括

热冲击导致RNA聚合酶II (Pol II) 转录过去的基因结尾. 这种读透转录与改变的Pol II速度,C端域 (CTD) 酸化和CPSF73活性有关,涉及RBBP6.

关键词:
科普:分子生物学在CPSF73中使用.在CTD化过程中,CTD化在RBBP6中,它是RBBP6.的RNA聚合酶II.热冲击是一种热冲击.终止 终止 终止 终止转录的阅读通过.

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