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Updated: Mar 1, 2026

Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry
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Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry

Published on: May 17, 2016

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单细胞蛋白活性分析揭示了异常的神经发生和IGF2-PI3K通路依赖性在MYOD1-突变性狂宫肌肉瘤中

Josephine K Dermawan1, Fabio Vanoli2, Henry Traux de Wardi3

  • 1Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA.

Science advances
|February 27, 2026
PubMed
概括

我们确定了一条关键的信号通路,涉及胰岛素样生长因子2 (IGF2),它驱动罕见的状细胞狂肌肉瘤 (SRMS). 抑制这种途径对治疗这种侵袭性癌症有希望.

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Preparation of Primary Myogenic Precursor Cell/Myoblast Cultures from Basal Vertebrate Lineages

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