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药物遗传学对布普罗生物激活的影响和重大抑郁障碍的临床结果

Evan D Kharasch1, Eric J Lenze2

  • 1Department of Anesthesiology, Duke University, Durham, North Carolina; Bermaride LLC, Durham, North Carolina.

The Journal of pharmacology and experimental therapeutics
|February 27, 2026
PubMed
概括

在CYP2B6的遗传变异显著影响身体如何处理布洛,影响药物清除和新陈代谢. 然而,这些CYP2B6多态性与抑郁症严重程度的变化或主要抑郁症患者的副作用没有相关性.

关键词:
布普罗皮昂 (Bupropion) 是一种在CYP2B6B6中.抑郁症 抑郁症 抑郁症氧布烯是一种氧烯.药物遗传学 药物遗传学立体化学是一种立体化学.

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