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Updated: Jul 30, 2026

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在活细胞和DILI中可视化线粒体单胺氧化酶动态,通过使用"ICT+ESIPT"机制的比度NIR探针进行可视化

Ting Cao1, Mengjin Li1, Hong Ma2

  • 1Key Laboratory of Magnetic Molecules & Magnetic Information Materials Ministry of Education, The School of Chemistry and Chemical Engineering, Shanxi Normal University, Taiyuan 030031, PR China.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
|February 27, 2026
PubMed
概括

研究人员开发了一种新的光探针Cy-1,用于实时监测单胺氧化酶 (MAO) 活性. 这种工具有助于了解肝损伤机制,并评估药物疗效.

关键词:
在DILI成像中使用DILI成像.线粒体向向的目标单胺氧化酸酶是一种单胺氧化酸酶.在NIR比率成像中使用NIR比率成像.正常/癌细胞分化ICT + ESIPT机制的使用

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Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...