在社会经济脆弱的老年人中,COVID后的认知功能障碍:来自巴西队列的发现
Danielle Calil de Sousa1,2, Arnaldo Santos Leite1, Luiz Gustavo Guimarães Sacramento1
1Universidade Federal de Minas Gerais, Faculdade de Medicina, Belo Horizonte MG, Brazil.
Arquivos de neuro-psiquiatria
|February 27, 2026
概括
长期的COVID可能会导致弱势群体的认知障碍. 这项研究发现,70.8%的社会经济地位较低的老年人经历了因冠状病毒病住院12-18个月后的认知问题.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 认知障碍是2019年冠状病毒疾病 (COVID-19) 的已知长期影响之一.
- 大多数关于COVID-19后认知障碍的证据来自高收入国家.
- 对社会经济弱势群体的影响仍未得到充分研究.
研究的目的:
- 研究来自社会经济弱势背景的老年人COVID-19住院治疗的长期认知影响.
- 为了确定与这一群体认知障碍相关的风险因素.
- 为了解COVID-19后的认知后果提供来自代表性不足的人口统计数据.
主要方法:
- 一组133名50岁以上的低学历和社会经济地位的50岁以上个人,因COVID-19住院治疗,在出院12-18个月后进行评估.
- 认知功能使用修改的认知状态电话采访 (TICS-M) 进行评估.
- 一个子组接受了进一步的认知和神经精神病学评估;认知障碍被定义为与年龄和教育调整规范的得分≤-1.5标准偏差.
主要成果:
- 认知障碍很普遍,影响了70.8%的参与者.
- 该样本包括老年人 (平均年龄65.3岁),主要是女性 (69.2%),受教育程度有限 (47.7% ≤4年上学) 和收入低 (83.6% ≤3个最低工资).
- 与认知障碍相关的因素包括较高的年龄,女性性别和低微症 (嗅觉受损).
结论:
- 认知障碍是COVID-19在社会经济脆弱的老年人住院治疗的常见和显著的长期后果.
- 这一发现凸显了针对这些人群的有针对性的研究和医疗保健支持的需要.
- 这项研究强调了COVID-19的后果对边缘化社区的影响不成比例.
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